47 jobs found in cambridge

About MOMA Therapeutics MOMA Therapeutics is a clinical-stage, next-generation precision medicine company dedicated to targeting highly dynamic proteins that underlie human disease via a small molecule approach, utilizing its proprietary KNOMATICTM platform. The platform was designed to exploit key vulnerabilities inherent to all dynamic proteins, namely their dependence on well-coordinated, stepwise changes in protein conformation. By focusing on genetically validated targets with high translation potential, MOMA is rapidly advancing its pipeline toward responses in the clinic. MOMA's lead assets include: MOMA-313 - A selective polymerase helicase theta inhibitor in Phase 1 MOMA - 989 - A next generation selective PARP1 inhibitor currently in IND enabling studies MOMA-341 - A selective Werner helicase inhibitor entering Phase 1 in 2025 MOMA's pre-clinical pipeline consisting of wholly-owned assets and discovery partnerships with Roche and Bayer. For more...

Company Summary: Quotient Therapeutics, Inc. is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need. Quotient Therapeutics, Inc. was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Seres Therapeutics (NASDAQ: MCRB), Sana Biotechnology (SANA), Axcella Health (AXLA), Indigo Agriculture, Generate Biomedicines, and Tessera Therapeutics. Position Summary: We are seeking a visionary Head of Biology to develop and advance an industry first pipeline informed by somatic genomics. The position has the unique opportunity to...

Basic Qualifications Requires excellent communication skills including public speaking, and the ability to handle difficult situations with diplomacy and judgment Minimum of 15 years of experience leading a large development enterprise. He or she will have an exceptional track record of leadership, engagement, and fundraising in large and complex universities or other similar institutions. The AVP/Dean will have worked successfully with a wide range of donors, leading to important and transformational gifts and the execution of highly sophisticated stewardship strategies. A bachelor's degree is required Ability to travel is required. Additional Qualifications and Skills Advanced degree is strongly preferred. Impeccable character and integrity; someone whom the institution and community can trust completely and without reservation. Superior interpersonal skills, a healthy sense of humor, and a supportive and accessible management style. Intelligence, compassion,...

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture. What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of...

About the Department Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Greater Boston and Greater Copenhagen reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients. The Position Diabetes, Obesity & MASH Global Research (DOMGR) is engaged in accelerating the path of core and novel cardiometabolic therapies for clinical development within Novo Nordisk. A main focus is discovery and evaluation...

About the Department Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Seattle reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients. The Position Diabetes, Obesity, & Mash Therapeutic Area (DOM TA) is engaged in accelerating the path of novel cardiometabolic therapies for clinical development within Novo Nordisk. A main focus is discovery and evaluation...

Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com. Job Description Summary: The Vice President and General Manager of Space Systems reporting to the President and CEO leads a transformation initiative to modernize the historic Innovation Factory, and align with growth markets. The Space Systems business area spans low earth orbit to deep space and everything in between and cuts across NASA, Intelligence Community, Department of Defense, and Commercial...

At DropGenie, we are making personalized possible. Personalized medicine requires experiments to be conducted at a scale that matches the diversity of patients while remaining cost-effective. We leverage electrical engineering, microfluidics, and materials science to miniaturize and parallelize complex genetic engineering workflows on a chip that can be seamless integrated into any lab automation ecosystem. Role Overview We seek an Engineering Lead / VP of Manufacturing to design, develop, and scale DropGenie's consumable manufacturing processes. This role is critical in driving manufacturing efficiency, quality, and cost-effectiveness while leading a high-performance team. Key Responsibilities Lead RCA, DFM, PFMEA, and statistical process control initiatives Oversee process validation and QC test protocols Develop and execute manufacturing strategies aligned with product scaling goals Manage vendors or establish in-house manufacturing capabilities Analyze...

The Opportunity Lesley University is seeking an experienced financial leader to join our team as the Associate Vice President of Financial Planning, Data, and Analysis (AVP). This is an exciting opportunity for a strategic thinker and change agent to serve as the architect and driver of financial models in collaboration with the CFO, playing a key role in shaping the university's financial future. Reporting to the Chief Financial Officer (CFO), the AVP will be responsible for developing and managing financial models, leading the university's annual budget process, and overseeing financial analysis and key metric reporting. The AVP will collaborate with university leadership to ensure the institution's financial health through data-driven decision-making, revenue and expense analysis, and the development of financial reporting improvements. This role will also serve as the primary liaison for the university's financial systems, ensuring system integrity and seamless integration...

Posting Description VICE PRESIDENT FOR INFORMATION TECHNOLOGY/CHIEF INFORMATION OFFICER (CIO), Office of the Executive Vice President and Treasurer , to lead the strategic direction and management of MIT's enterprise digital infrastructure; facilitate information technology across the Institute, supporting systems, infrastructure, and platforms; collaborate with internal and external partners, including the Office of Research Computing (ORCD), the Massachusetts Green High Performance Computing Center (MGHPCC), and MIT's Lincoln Laboratory; champion cybersecurity, integrate modern administrative systems, and drive digital transformation; oversee customer-focused IT services and manage resources sustainably; co-chair the Information Technology Governance Committee and serve on the MGHPCC Board; and report to the Executive Vice President and Treasurer (EVPT) and serve on the President's Academic Council. Job Requirements REQUIRED: Master's degree or equivalent years of experience...

Description Essential Functions: Leadership Direct or coordinate an organization's financial or budget activities to fund operations, maximize investments, or increase efficiency. Confer with board members, organization officials, or staff members to discuss issues, coordinate activities, or resolve problems. Direct or coordinate activities of businesses or departments concerned with production, pricing, sales, or distribution of products. Provides Senior Level Leadership of departments including Information Technology, Revenue Cycle, Payroll Services, Dietary Services, Rehabilitation Services and Materials Management. Independence Analyze operations to evaluate performance of a company or its staff in meeting objectives or to determine areas of potential cost reduction, program improvement, or policy change. Direct, plan, or implement policies, objectives, or activities of organizations or businesses to ensure continuing operations, to maximize returns on...

Position Summary: The Senior Director/Vice President of Clinical Operations will be responsible for the planning, implementation, execution and management of clinical studies by overseeing day-to-day operations and directly managing and working with outside Clinical Research Organizations and academic institutions. Additionally, will work closely with cross-functional teams, senior leadership, and external stakeholders to meet clinical milestones while maintaining high-quality standards, timelines, and budgets. The candidate must thrive working in a fast-paced, innovative environment while remaining flexible, proactive, resourceful and efficient. Ability to analyze complex issues to develop relevant and realistic plans and recommendations. Responsibilities: Develop and execute clinical operations strategies aligned with the company's overall goals and objectives. Plan and communicate with cross-functional teams to ensure proper initiation, execution, and conduct of...

Scholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on advancing innovative treatments where protein growth factors are fundamental. Over the past decade, the company has created a pipeline with the potential to advance the standard of care for neuromuscular disease, cardiometabolic disorders, cancer, and other conditions where growth factor-targeted drugs can play a transformational role. Scholar Rock is the only company to show clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). This commitment to unlocking fundamentally different therapeutic approaches is powered by broad application of a proprietary...

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture. What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of...

Head Clinical Pharmacology and Pharmacometrics (Executive Director - Vice President) Application Deadline: 28 May 2025 Department: Clinical Development Employment Type: Full Time Location: Cambridge, MA Description Company Overview At Merus, we are advancing leading-edge, targeted treatments using our pioneering multispecific antibody generating technologies, Multiclonics®, to address the unmet needs of patients with various types of cancer. Working at Merus gives you the opportunity to contribute to our mission of closing in on cancer. We care deeply about improving patients' lives. This is why we are committed to getting this right, with a global and diverse team of highly qualified professionals. We have bold aspirations because the need is great, and the patients are waiting. Join us and make an impact. Your role: Merus is seeking a Head of Clinical Pharmacology and Pharmacometrics to serves as the functional leader of the Translational Pharmacology,...

Company Overview Beam Therapeutics is a clinical stage biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam has used to advance a diversified portfolio of base editing programs, including four programs to the clinic. Beam's lead program, BEAM-101 has recently demonstrated clinical validation in Sickle cell disease through upregulation of fetal hemoglobin in patients. Beam is...

Description Position at EF Adventures Are you a seasoned general manager with a strong background in digital marketing, a passion for adventure, and a proven track record of scaling businesses? For over 30 years, EF's Adult Travel divisions have been the gateway to unforgettable experiences, guiding travelers from all walks of life across the globe. From college students to retirees, solo adventurers to entire families, we believe the best way to learn about the world is to experience it firsthand. Every day, we strive to help as many people as possible embark on their next great adventure. The Role EF World Journeys is looking for a dynamic Executive Vice President to take our newly launched active adventure tour product, EF Adventures, to new heights. This role is all about scaling the business, driving volume, and making it profitable. If you thrive in a fast-paced, entrepreneurial environment and have a strong background in sales and digital marketing, this is the...

Amylyx was started in 2013 by two Brown University students who had an ambitious goal: to improve the lives of people with neurodegenerative diseases by addressing the root cause. Today, Amylyx is a pharmaceutical company based in Cambridge, Massachusetts, that is dedicated to the discovery and development of potential treatments for diseases including Wolfram syndrome, progressive supranuclear palsy (PSP), and amyotrophic lateral sclerosis (ALS). At Amylyx, we're bringing together talented people like you who are guided by our values to be Audacious, Curious, Authentic, Engaging and Accountable. Our mission would not be possible without each individual perspective within our team. It's a culture that uses unconventional thinking for unsolved problems. Rediscover your purpose and reimagine your career at a company whose founders, mission, and culture are unlike any other in life sciences-in all the best ways. THE OPPORTUNITY The Senior Vice President (SVP) of Clinical...

What if... We could harness the power of Flagship's scientific platforms and create novel treatment options that benefit more patients, sooner? Pioneering Medicines, an initiative of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability focused on conceiving and developing life-changing treatments for patients by harnessing the power of Flagship's scientific platforms and applying those innovative approaches to serious diseases with unmet medical need. Unique to Pioneering Medicines' approach is the opportunity to combine platforms and partner with pharma companies to create truly novel and transformative treatments. Position Summary: Pioneering Medicines is seeking a curious and driven Vice President of Project Leadership and Development with experience in pharma/biotech. This role involves leading early clinical development for multiple assets in the Pioneering Medicines portfolio and earlier projects in the respiratory and immunology sectors,...

Job Description Nearly 37 million Americans are currently affected by Chronic Kidney Disease. 37 million. At Akebia we take that number very seriously and every day we come to work, with the purpose of bettering the lives of each person impacted by kidney disease and the renal community that serves them. Our tenacious, passionate employees' challenge the status quo and work to develop unique therapeutics that have the potential to set new standards of care for people living with kidney disease. This is life-changing work, and we are all in, are you? Akebia is looking for a VP, Legal - Life Sciences to join its fast-paced and collaborative legal and compliance team. The VP, Legal - Life Sciences will report to the SVP, Legal & General Counsel and serve as the business partner for the following functions at Akebia: research and development, manufacturing and supply, business development, alliance management and procurement. As a member of Akebia's Management Team and a part...